Achieving significant changes in medical practice
Since 1991, we have been working towards a world free of GI cancer. We put patients with GI cancer at the centre of our research, saving and improving lives by accelerating the pace of discoveries that lead to cures.
We are proud that our independent, patient-centred research has been integral to worldwide changes in medical practice. Our clinical trials have improved outcomes for people with GI cancer and provided access to cutting-edge treatments and high care support not otherwise available.
We have extended life expectancy for patients with GI cancer by testing:
- Oral chemotherapy as an alternative to intravenous therapies
- New drug treatments
- Targeted therapies and personalised therapy
- Preoperative chemo radiation
- Novel combinations of treatments
We have improved quality-of-life for patients by:
- Reducing side effects by a different combination of chemotherapies
- Identifying patients who do not benefit from certain therapies
- Demonstrating that a shorter duration of treatment is equally efficacious but less toxic in the adjuvant treatment of colorectal cancer
We have tested new targeted therapies:
- Demonstrating that a drug that acts on tumour growth is safe and active in oesophageal cancer
- Showing that a monoclonal antibody treatment is likely to benefit selected patients with bile duct cancer
We have established surgical guidelines to:
- Improve survival outcomes for pancreatic cancer patients
We are now starting to test preventative therapies in GI cancer.