- AG9401
Trial Status
Closed
Cancer Type
Colorectal Cancer
If you think this trial is relevant to your situation, please contact your Cancer Specialist to discuss further.
Protocol Title
A randomised trial of early chemotherapy in asymptomatic metastatic colorectal cancer.
Purpose of the Study
People with advanced colon cancer sometimes feel completely well when they are first diagnosed. This study asks the question, “Is it better to start chemotherapy immediately – causing serious side-effects – or delay until symptoms appear?” The results of this study demonstrated that delaying chemotherapy was as safe as giving treatment straightaway and allowed better quality of life in the meantime.
Principal Investigator
Prof Stephen Ackland
Funding
Pharmacia (Pty) Limited (Australia)
Trial Status
Closed
Cancer Type
Colorectal Cancer
If you think this clinical trial may be relevant to your patient or to discuss further, please contact the Clinical Trial team.
Publication Reference
Ackland SP, Jones M, Tu D, Simes J, Yuen J, Sargeant A-M, Dhillon H, Goldberg RM, Abdi E, Shepherd L, Moore MJ. A meta-analysis of two randomised trials of early chemotherapy in asymptomatic metastatic colorectal cancer. British Journal of Cancer 2005; 93: 1235–1243.
Conference Presentation Reference
Ackland S, Moore M, Jones M, Tu D, Simes R, Yuen J, Sargeant A, Dhillon H, Goldberg R, Abdi E, Shepherd L A. Meta-analysis of two randomised trials of early chemotherapy in asymptomatic metastatic colorectal cancer. American Society of Clinical Oncology Annual Meeting; 12–15 May 2001; San Francisco.
Aim
People with advanced colon cancer sometimes feel completely well when they are first diagnosed. This study asks the question, “Is it better to start chemotherapy immediately – causing serious side-effects – or delay until symptoms appear?” The results of this study demonstrated that delaying chemotherapy was as safe as giving treatment straightaway and allowed better quality of life in the meantime.
Principal Investigator
Professor Stephen Ackland, Medical Oncologist, Newcastle Calvary Mater Hospital NSW
Funding
Pharmacia (Pty) Limited (Australia)
