Multi-centre, prospective cohort study. This study will review the feasibility and potential benefit of instituting routine comprehensive molecular profiling of ABC using either fresh frozen or archival tissue obtained at the time of routine diagnostic tests such as percutaneous biopsy, ERCP or EUS. Read More

Developing and applying artificial intelligence (AI) based image analysis for scoring PD-L1 immunohistochemistry in gastric cancer Read More

This study will investigate both Sacral nerve stimulation (SNS) and Transanal irrigation (TAI) in patients with severe low anterior resection syndrome (LARS) symptoms against non-surgical management. The trial will investigate whether these treatments can improve patients’ symptoms, QoL and investigate the cost implications. Read More

STOPNET - Comparison of patient outcomes with or without continuation of somatostatin injections after the commencement of Peptide Receptor Radionuclide Therapy (PRRT) Read More

BIOMARCER-2 - Biomarker informed optimal management of advanced RAS wild type colorectal cancer in right sided disease Read More

A phase II trial evaluating EGFR inhibition with HDAC inhibition in refractory colorectal cancer Read More

Avelumab plus fluoropyrimidine-based chemotherapy as adjuvant treatment for stage III dMMR or POLE exonuclease domain mutant colon cancer: A phase III randomised study Read More