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An organoid sensitivity testing driven umbrella study for patients with chemorefractory metastatic colorectal cancer. Read More
This study aims to demonstrate that a chemotherapy decision incorporating ctDNA results in addition to standard pathologic risk assessment will reduce the number of patients receiving adjuvant chemotherapy. Read More
The aim of ALT GIST is to determine whether an alternating treatment approach - using Imatinib and Regorafenib - improves disease control in patients with advanced (metastatic) gastrointestinal stromal tumours. Read More
The aim of ACTICCA-1 is to determine whether treating patients with chemotherapy following surgery for cancer of the biliary tract helps to reduce cancer recurrence. Read More
The purpose of TOPGEAR is to investigate the benefit of adding radiation (chemoradiotherapy) to chemotherapy and surgery to treat and improve the overall survival in patients undergoing surgery for resectable stomach cancer. Read More
The aim of NABNEC is to determine the safety and efficacy of carboplatin plus nab-paclitaxel in comparison with the current standard chemotherapy treatment plan (carboplatin plus etoposide) for advanced gastrointestinal neuroendocrine carcinomas (NECs). Read More
The ASCOLT study will evaluate the safety and effectiveness of low-dose aspirin compared to placebo in reducing recurrence of colorectal cancer and improving survival for patients with Dukes C and high-risk Dukes B colorectal cancer. Read More
The aim of this study is to investigate the activity of anti-EGFR monotherapy, or combined with infusional 5FU, in a molecularly selected, elderly patient population with metastatic colorectal cancer. Read More
The aim of the CONTROL NETS trial is to find the optimal treatment to improve disease control in patients with advanced Neuroendocrine tumours (NETs). Read More