Clinical Trials - Translational Research Studies

The clinical trials listed in this section are either open to patient recruitment or in development. For each trial, an overview of the study design is provided together with a brief explanation of the trial objectives. Members can review the Trial Report in the Members Area.

Filter AGITG trials by

ASCOLT circulating tumour DNA (“ActDNA”) translational study: prediction of minimal residual disease in a large Phase III randomised adjuvant colorectal cancer trial. Read More

Multicentre non-interventional prospective cohort study to identify potential RNA and DNA-based risk factors associated with immune-related adverse events (irAEs) Read More

Developing and applying artificial intelligence (AI) based image analysis for scoring PD-L1 immunohistochemistry in gastric cancer. Read More

BIOMARCER-2 - Biomarker informed optimal management of advanced RAS wild type colorectal cancer in right sided disease Read More

CONTROL NETs translational sub-study will investigate the gene MGMT and aims to predict who will benefit by having chemotherapy with PRRT, and who can have PRRT on its own. Read More

Understanding the effect of chemotherapy on microbial composition of pancreatic ductal adenocarcinoma (PDAC) patients Read More

Radiological And subjective measures of Nutrition, Diet and sarcOpenia - a Masterplan Substudy (RANDOMS) Read More

This Translational study aims to provide a second tier screening test to identify the patients at the highest risk of CRC to fast track their diagnosis. Read More

A translational substudy of NEO-IMPACT to investigate the longitudinal evolution of the pancreas cancer microbiome when exposed to chemo-immunotherapy pre-operatively. Read More

This translational study aims to determine what impact STING levels have on the ability for gastro-oesophageal cancers to respond to treatment, how this impacts the immune response to cancer and ultimately the ability to survive. Read More

The OMEGCA study is a prospective trial to develop a sensitive assay to detect clinically occult peritoneal metastases. Read More

Predicting ChemoRadiotherapy Sensitivity in Rectal Cancer Organoids (PRoSecCO) Read More