Genesis of a clinical trial

To successfully obtain funding for academic research and the establishment of a clinical trial takes a considerable amount of effort, time and collaboration across multi-disciplinary teams.

Click on the images below to follow the genesis of several AGITG trials from the identification of a problem to obtaining funding and support:

OXTOX

OXTOX is investigating whether the tablet ibudilast can reduce one of the symptoms of chemotherapy, acute neuropathy, in people being treated for advanced colorectal cancer.

RENO

The aim of this study is to assess the safety of the 'watch and wait' approach before surgery for people with rectal cancer.

NABNEC

The NABNEC trial is a randomised study which will assess the most promising treatment for patients with neuroendocrine tumours (NETs).

MONARCC

The MONARCC trial seeks to determine what the best initial treatment is for an elderly patient population that may not withstand the side effects of commonly used combination chemotherapy regimens.

VADER

The VADER trial will test the effectiveness of a drug called sodium valproate in first-line treatment of patients with colorectal cancer.