The GI Cancer Trials Research Prioritisation and Development Framework is a transparent process which fosters the development and refinement of concepts as they progress through each GCT Research Committee. The concepts listed below have been prioritised to progress through the Framework by the Research Executive Committee.
If you have any questions related to the information below, please contact us at research@gicancer.org.au.
CORONET
Investigators: A/Prof David Chan and Professor Nick Pavlakis
Lead Sponsor: GI Cancer Trials
Tumour: Progressive pancreatic neuroendocrine neoplasms (pNENs)
Phase 2/3
Location: National
Stage of Development: Awaiting funding
DYNAMIC-IV
Investigators: Prof Jeanne Tie, A/Prof Amitesh Roy and Dr John Mak
Lead Sponsor: GI Cancer Trials
Tumour: Resectable colorectal cancer with liver-only metastases
Phase 2/3
Location: International & National
Stage of Development: Awaiting funding
COMPASS (Formerly ORBIT)
Investigators: Dr Julia Freckelton, Prof Niall Tebbutt
Lead Sponsor: GI Cancer Trials
Tumour: Early-Onset Gastrointestinal (GI) cancers: colorectal, gastric, pancreatic, biliary, or other GI malignancies.
Phase Pilot Study
Location: National
Stage of Development: Embryonic, Awaiting Funding
STEADY-CRT
Investigators: A/Prof Hannah Wardill, Prof Joanne Bowen and Prof Chris Karapetis
Lead Sponsor: GI Cancer Trials
Tumour: Anal Cancer
Phase 2
Location: National
Stage of Development: Embryonic, Awaiting Funding
PALM-RC
Investigators: Dr Norma Bulamu, A/Prof Amitesh Roy, Dr Paul Hollington, Dr Muktar Ahmed, A/Prof Amy Brown, Melissa Bodenham, Nicole Kroesche, A/Prof Erin Symonds, Prof Billingsley Kaambwa
Lead Sponsor: GI Cancer Trials
Tumour: Rectal Cancer
Phase Pilot
Location: National
Stage of Development: Embryonic, Awaiting Funding
NEOCYT
Investigators: Prof Tim Price, Dr Chris Lauder, Dr Mei Chan, Dr Linh Van
Lead Sponsor: GI Cancer Trials
Tumour: pMMR adenocarcinoma with primary sites being colorectal or appendix
Phase Pilot/signal seeking
Location: National
Stage of Development: Embryonic, Awaiting Funding
CIRCADIAN
Investigators: Dr John Mak, Prof Chris Karapetis, Dr Ben Lawrence
Lead Sponsor: GI Cancer Trials
Tumour: dMMR/MSI-high luminal GI cancers (colorectal, small bowel, gastroesophageal)
Phase 3
Location: International & National
Stage of Development: Awaiting Funding