INTERNATIONAL ASSOCIATION FOR THE STUDY OF LUNG CANCER WORLD CONFERENCE ON LUNG CANCER, SEPTEMBER 23RD -26TH TORONTO, ON, CAN

Pulmonary Neuroendocrine (Carcinoid) Tumors: CommNETs/NANETS Endorsement and Update of the ENETs Best Practice Consensus

Singh S., Bergsland E.K., Card C.M., Hope T.A., Kunz P.L., Laidley D.T., Lawrence B., Leyden S., Metz D.C., Michael M., Modahl L.E., Murehaug S., Padda S.K., Pommier R.F., Ramirez R.A., Soulen M., Strosberg J., Thawer A., Wei B., Xu B., Segelov E. Lung Neuroendocrine (Carcinoid) Tumors: CommNETS/NANETS Endorsement and Update of the ENETS Best Practice Consensus.

Brief Presentation Description:

The Commonwealth Neuroendocrine Tumour Collaboration (CommNETS) and North American Neuroendocrine Tumor Society (NANETS) collaborated to provide updated guidelines on the diagnosis and management of lung neuroendocrine tumors (NETs). Lung NETs are rising in incidence and prevalence, yet there is very limited lung NET specific literature. The European Neuroendocrine Tumor Society (ENETS) in 2015 published the most recent expert consensus and recommendations for best practice for lung NETs. The quality of the methods and content of the ENETs publication was confirmed using the AGREE II Rigour of Development subscale (agreetrust.org). The CommNETS/NANETS collaboration involved a multidisciplinary 22-member committee, with the mission to provide an endorsement and update of the ENETs guidelines. All statements were graded using Oxford Criteria (CEBM.net). The committee reviewed and considered 230 updated studies from a systematic literature search in order to endorse, modify, remove or add recommendations. Of the 52 ENETS statements, 40% were endorsed, 58% were modified, one was removed and four were added. The consensus update encompassed practice-changing modifications, and also refined grades of recommendation and statements. The consensus update addressed a broad range of topics, including epidemiology, pathology, diagnosis, treatment and follow-up. The consensus update also emphasized the importance of lung NET specific research and patient-centered care along with identifying specific future directions for research.

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