working parties

Summary of the 2018 Open Working Party Meetings

On 11 May, the AGITG held its Annual General Meeting coinciding with an Open Working Parties Meeting.

The Working Parties represent the disciplines of medical oncology, surgery, radiation oncology, statistics and translational science. They meet face-to-face bi-monthly to identify gaps in research, develop new clinical research concepts and review the scientific merit of research proposals.

Open Lower GI Working Party Meeting

The Lower GI Working Party focusses on cancer of the bowel, rectum and anus. The Open Meeting reviewed the AGITG clinical trials and research that are currently open.

The DYNAMIC-Rectal study, which is examining the effectiveness of ctDNA analysis in advanced colorectal cancer patients, aims to recruit 408 patients over the next 2-3 years. The SPAR trial is also open and has randomised its first patient. The RENO trial is currently in start-up.

The Working Party also reviewed gaps in research in rectal cancer. The TRIGGER study was examined as a new concept. Ultimately, it was decided that the AGITG would not support the study in its current format as it competed with SPAR and the proposal was ambitious.

Open Upper GI Working Party Meeting

The Upper GI Working Party focuses on cancers of the oesophagus, gallbladderpancreas, stomach and liver.

The Open Meeting reviewed the DYNAMIC-Pancreas study, which is investigating the feasibility of ctDNA analysis in pancreatic cancer patients.

The Working Party also discussed the potential of utilising a malnutrition screening tool for pancreatic cancer trials, and gaining consensus on an algorithm to use.

Hepatocellular Carcinoma

There was an overview of current trials in hepatocellular carcinoma (HCC) led by Associate Professor Lara Lipton. Associate Professor Simone Strasser, a hepatologist with RPA Sydney, provided an overview of current trials conducted in Australia in this area. The group concluded that there would be mutual benefit in trials which involved both oncologists and hepatologists, and that the Upper GI Working Party would invite HCC investigators to join the group.

More information on our Working Parties is available here.