Gastro-intestinal (GI) cancer is the most common form of cancer. More than 28,800 Australians are diagnosed with GI cancer each year and 38 Australians die from the disease each day. Major advances in treating GI cancers and improving patient quality of life are possible because of research and clinical trials. We improve the health and quality of life of patients with Gastro-Intestinal cancer by developing and conducting impartial and collaborative multi-disciplinary trials.